(Dry Gangrene; Gas Gangrene; Organ or Tissue Death; Wet Gangrene)


Gangrene is the progressive death of body tissue resulting from infection and a lack of blood supply. When the blood supply is cut off, the tissue does not get enough oxygen and begins to die.
Gangrene can be internal or external. The 2 most common types of gangrene are:
A rare wet type, called gas gangrene or clostridial myonecrosis, develops from specific bacteria deep inside the body. Gas gangrene can be a result of surgery or trauma.


Gangrene is caused by infection or a reduced blood supply to tissues.

Risk Factors

Gangrene is more common in older adults.
Other factors that may increase your chance of gangrene include:


External gangrene may cause:
Internal gangrene may cause:
If the gangrene is widespread, sepsis can occur.
Gangrene of the Foot
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You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with:
Images may be taken of your bodily structures. This can be done with:


Treatment of gangrene includes:


To help reduce your chance of gangrene:


American Diabetes Association

Family Doctor—American Academy of Family Physicians


Canadian Diabetes Association

Health Canada


A quick summary of the 6 types of necrosis. Pathology Student website. Available at: Accessed August 5, 2015.

Clostridial myonecrosis. EBSCO DynaMed website. Available at: Updated October 1, 2014. Accessed August 5, 2015.

Fujiwara Y, Kishida K, Terao M, et al. Beneficial effects of foot care nursing for people with diabetes mellitus: an uncontrolled before and after intervention study. J Adv Nurs. 2011;67(9):1952-1962.

Gangrene. NHS Choices website. Available at: Updated January 27, 2014. Accessed August 5, 2015.

Sepsis in adults. EBSCO DynaMed website. Available at: Updated July 25, 2014. Accessed September 29, 2014.

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